Description

6-Isoquinolinol,1-(4-Fluorophenyl)-1,2,3,4-Tetrahydro-(9Ci) is a high-value, fluorinated tetrahydroisoquinoline derivative, a privileged scaffold in modern medicinal chemistry. This compound matters as a critical pharmaceutical intermediate for the research and development of novel therapeutic agents, offering a versatile building block for structure-activity relationship (SAR) studies. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors, as well as by fine chemical suppliers serving these industries.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of central nervous system (CNS) active drugs, including potential antipsychotics and antidepressants.
• Medicinal Chemistry Research: Used as a core scaffold for designing and synthesizing novel bioactive molecules targeting various receptors and enzymes.
• Chemical Biology Probes: Employed in the synthesis of tool compounds for studying biological pathways and target validation.
• Process Chemistry & Scale-Up: Utilized in route scouting and optimization for the commercial-scale production of active pharmaceutical ingredients (APIs).
• Library Synthesis: A valuable building block for generating diverse compound libraries for high-throughput screening (HTS) in drug discovery.
• Academic Research: Used in universities and research institutes for studies in organic synthesis methodology and heterocyclic chemistry.

Basic Information

Product Name	6-Isoquinolinol,1-(4-Fluorophenyl)-1,2,3,4-Tetrahydro-(9Ci)
CAS No.	596791-47-8
Molecular Formula	C₁₅H₁₄FNO
Molecular Weight	243.28 g/mol
Synonyms	1-(4-Fluorophenyl)-1,2,3,4-tetrahydro-6-isoquinolinol; 6-Hydroxy-1-(4-fluorophenyl)-1,2,3,4-tetrahydroisoquinoline; 1-(4-Fluorophenyl)-6-hydroxy-1,2,3,4-tetrahydroisoquinoline; 6-Isoquinolinol, 1-(4-fluorophenyl)-1,2,3,4-tetrahydro- (9CI); 1-(p-Fluorophenyl)-1,2,3,4-tetrahydro-6-isoquinolinol; 1-(4-Fluorophenyl)-1,2,3,4-tetrahydroisoquinolin-6-ol; 6-Hydroxy-1-(p-fluorophenyl)-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our 6-Isoquinolinol,1-(4-Fluorophenyl)-1,2,3,4-Tetrahydro-(9Ci) is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring the material meets the stringent requirements for pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.