Description

1H-Indole,2,3-Dihydro-5-Methoxy-2-(2-Pyridinyl)-(9Ci) is a high-purity, advanced pharmaceutical intermediate belonging to the indole alkaloid class. This compound matters for its critical role as a sophisticated building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including potential candidates for neurological and oncological applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Organic Synthesis Building Block: Used in complex multi-step syntheses to construct fused heterocyclic systems with potential biological activity.
• Biochemical Research: Employed in the study of enzyme inhibitors and receptor ligands due to its privileged indole-pyridine structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.

Basic Information

Product Name	1H-Indole,2,3-Dihydro-5-Methoxy-2-(2-Pyridinyl)-(9Ci)
CAS No.	595545-69-0
Molecular Formula	C15H14N2O
Molecular Weight	238.29 g/mol
Synonyms	5-Methoxy-2-(pyridin-2-yl)-2,3-dihydro-1H-indole; 2-(2-Pyridinyl)-5-methoxy-2,3-dihydro-1H-indole; 5-Methoxy-2-(2-pyridyl)indoline; 2,3-Dihydro-5-methoxy-2-(2-pyridinyl)-1H-indole; 1H-Indole, 2,3-dihydro-5-methoxy-2-(2-pyridinyl)-; (9CI)
EINECS	Contact for details

Quality Control

Our 1H-Indole,2,3-Dihydro-5-Methoxy-2-(2-Pyridinyl)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere when appropriate to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.