Description

1H-Indole,2,3-Dihydro-5-(1-Methylethyl)-2-(4-Pyridinyl)-(9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for designing and optimizing new molecular entities in drug discovery programs.
• Process Development & Scale-Up: Used in the development and optimization of synthetic routes for potential commercial API manufacturing.
• Reference Standard: Employed as an analytical standard for quality control and method validation in pharmaceutical analysis.
• Academic & Contract Research: Utilized in university and CRO settings for exploratory synthesis and structure-activity relationship (SAR) studies.

Basic Information

Product Name	1H-Indole,2,3-Dihydro-5-(1-Methylethyl)-2-(4-Pyridinyl)-(9Ci)
CAS No.	594818-10-7
Molecular Formula	C16H18N2
Molecular Weight	238.33 g/mol
Synonyms	5-Isopropyl-2-(pyridin-4-yl)-2,3-dihydro-1H-indole; 2-(4-Pyridinyl)-5-(1-methylethyl)-2,3-dihydro-1H-indole; 5-Isopropyl-2-(4-pyridyl)indoline; 2,3-Dihydro-5-isopropyl-2-(4-pyridinyl)-1H-indole; 594818-10-7
EINECS	Contact for details

Quality Control

Our 1H-Indole,2,3-Dihydro-5-(1-Methylethyl)-2-(4-Pyridinyl)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles suitable for pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.