Description

1H-Indole,5-Chloro-2,3-Dihydro-2-(4-Pyridinyl)-(9Ci) is a high-purity, advanced pharmaceutical intermediate belonging to a class of complex heterocyclic compounds. This compound matters as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting the central nervous system and oncology. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise chemical scaffold to develop and scale up next-generation drug candidates, ensuring process consistency and regulatory compliance.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of potent drug candidates, especially those with indole and pyridine pharmacophores.
• Medicinal Chemistry Research: Used extensively in R&D for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• API Development: Integral to the process development and optimization stages for new Active Pharmaceutical Ingredients, requiring high chemical purity.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Biochemical Tool Compound: May be utilized in biochemical assays as a reference standard or probe to study specific biological pathways.
• Academic Research: Employed in university and institutional laboratories for advanced organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	1H-Indole,5-Chloro-2,3-Dihydro-2-(4-Pyridinyl)-(9Ci)
CAS No.	593234-55-0
Molecular Formula	C₁₃H₁₁ClN₂
Molecular Weight	230.69 g/mol
Synonyms	5-Chloro-2-(pyridin-4-yl)-2,3-dihydro-1H-indole; 2-(4-Pyridinyl)-5-chloro-2,3-dihydro-1H-indole; 5-Chloro-2-(4-pyridyl)indoline; 593234-55-0; 5-Chloro-2-(4-pyridinyl)-2,3-dihydro-1H-indole; 2,3-Dihydro-5-chloro-2-(4-pyridinyl)-1H-indole
EINECS	Contact for details

Quality Control

Our 1H-Indole,5-Chloro-2,3-Dihydro-2-(4-Pyridinyl)-(9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive compound.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.