Description

1H-Indole,7-Chloro-2,3-Dihydro-2-(2-Pyridinyl)-(9Ci) is a high-purity, advanced pharmaceutical intermediate belonging to a class of complex heterocyclic compounds. This compound is of significant value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Active Pharmaceutical Ingredient (API) Development: Serves as a building block in the multi-step synthesis of potential APIs, especially in the indole and pyridine chemical classes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Biochemical Research: May be utilized in the study of enzyme inhibitors or receptor ligands due to its specific heterocyclic structure.

Basic Information

Product Name	1H-Indole,7-Chloro-2,3-Dihydro-2-(2-Pyridinyl)-(9Ci)
CAS No.	591758-86-0
Molecular Formula	C13H11ClN2
Molecular Weight	230.69 g/mol
Synonyms	7-Chloro-2-(pyridin-2-yl)-2,3-dihydro-1H-indole; 2-(7-Chloro-2,3-dihydro-1H-indol-2-yl)pyridine; 7-Chloro-2-(2-pyridyl)indoline; 1H-Indole, 7-chloro-2,3-dihydro-2-(2-pyridinyl)-; 591758-86-0; 7-Chloro-2-(2-pyridinyl)-2,3-dihydro-1H-indole
EINECS	Contact for details

Quality Control

Our 1H-Indole,7-Chloro-2,3-Dihydro-2-(2-Pyridinyl)-(9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent degradation. Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.