Description

1H-Indole,5,7-Difluoro-2,3-Dihydro-2-(4-Pyridinyl)-(9Ci) is a high-purity, advanced pharmaceutical intermediate featuring a unique indole-pyridine hybrid scaffold. This compound is critical for research and development in medicinal chemistry, enabling the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and CNS drug discovery.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates targeting protein kinases and other enzymes.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its privileged heterocyclic structure.
• Chemical Biology Probes: Serves as a core scaffold for developing molecular probes to study biological pathways and target validation.
• Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection.
• Material Science: Investigated as a precursor for organic electronic materials and functional polymers.

Basic Information

Product Name	1H-Indole,5,7-Difluoro-2,3-Dihydro-2-(4-Pyridinyl)-(9Ci)
CAS No.	591721-09-4
Molecular Formula	C₁₃H₁₀F₂N₂
Molecular Weight	232.23 g/mol
Synonyms	5,7-Difluoro-2-(pyridin-4-yl)-2,3-dihydro-1H-indole; 2-(4-Pyridinyl)-5,7-difluoro-2,3-dihydro-1H-indole; 5,7-Difluoro-2-(4-pyridyl)indoline; 2-(Pyridin-4-yl)-5,7-difluoro-2,3-dihydro-1H-indole; 591721-09-4; 4-(5,7-Difluoro-2,3-dihydro-1H-indol-2-yl)pyridine
EINECS	Contact for details

Quality Control

Our 1H-Indole,5,7-Difluoro-2,3-Dihydro-2-(4-Pyridinyl)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with material suitable for research use and can discuss scalable production under cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.