Description

1H-Indole-3-Carboxaldehyde,2-(1,1-Dimethylethyl)-5-(Trifluoromethyl)-(9Ci) is a high-value, multi-functional indole derivative that serves as a critical advanced intermediate in organic synthesis. Its unique molecular architecture, featuring a sterically hindered tert-butyl group and an electron-withdrawing trifluoromethyl substituent, makes it indispensable for constructing complex heterocyclic frameworks. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in the development of receptor modulators and enzyme inhibitors.
• Agrochemical Research: Used in the creation of advanced pesticides and herbicides, leveraging the stability and bioactivity of the indole core.
• Material Science: Serves as a precursor for functional organic materials, including ligands for catalysis and components for organic electronics.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO laboratories.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	1H-Indole-3-Carboxaldehyde,2-(1,1-Dimethylethyl)-5-(Trifluoromethyl)-(9Ci)
CAS No.	591720-26-2
Molecular Formula	C₁₄H₁₄F₃NO
Molecular Weight	269.26 g/mol
Synonyms	2-tert-Butyl-5-(trifluoromethyl)-1H-indole-3-carboxaldehyde; 2-(tert-Butyl)-5-(trifluoromethyl)-1H-indole-3-carbaldehyde; 5-(Trifluoromethyl)-2-tert-butylindole-3-carboxaldehyde; 2-tert-Butyl-5-trifluoromethylindole-3-carboxaldehyde; 2-(1,1-Dimethylethyl)-5-(trifluoromethyl)-1H-indole-3-carboxaldehyde; 591720-26-2; 2-tert-Butyl-5-(trifluoromethyl)indole-3-carbaldehyde
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our fine chemical intermediates. Each batch of 1H-Indole-3-Carboxaldehyde,2-(1,1-Dimethylethyl)-5-(Trifluoromethyl)-(9Ci) is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. Our quality management system is designed to meet the exacting standards required for research and cGMP manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere when not in use to prevent degradation and ensure long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.