Description

1H-Indol-5-Amine,2,3-Dihydro-2-Methyl-,(2R)-(9Ci) is a chiral, substituted indoline derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with specific stereochemical configurations.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug candidates, particularly those targeting neurological and cardiovascular disorders.
• Agrochemical Research: Used in the development of novel pesticides and herbicides where specific stereochemistry influences biological activity.
• Asymmetric Synthesis: Employed as a chiral auxiliary or scaffold in catalytic asymmetric reactions to induce enantioselectivity.
• Fine Chemical Production: Serves as a building block for the manufacture of specialty dyes, pigments, and advanced materials.
• Biochemical Research: Used in academic and industrial R&D for studying enzyme inhibitors and receptor ligands.
• Process Chemistry Development: Integral for scaling up synthetic routes in pilot plants and commercial manufacturing of chiral molecules.

Basic Information

Product Name	1H-Indol-5-Amine,2,3-Dihydro-2-Methyl-,(2R)-(9Ci)
CAS No.	590421-11-7
Molecular Formula	C9H12N2
Molecular Weight	148.21 g/mol
Synonyms	(2R)-2-Methyl-2,3-dihydro-1H-indol-5-amine; (R)-2-Methylindolin-5-amine; (R)-5-Amino-2-methylindoline; 2,3-Dihydro-2-methyl-1H-indol-5-amine, (2R)-; (R)-5-Amino-2-methyl-2,3-dihydro-1H-indole; 590421-11-7; (R)-2-Methyl-2,3-dihydro-1H-indol-5-ylamine
EINECS	Contact for details

Quality Control

Our 1H-Indol-5-Amine,2,3-Dihydro-2-Methyl-,(2R)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure compliance with stringent specifications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.