Description

5-{[1-(2-Fluorobenzyl)-1H-Indol-3-Yl]Methylidene}-1,3-Dimethyl-2-Thioxodihydropyrimidine-4,6(1H,5H)-Dione is a high-purity, non-nucleoside heterocyclic compound featuring a complex molecular architecture. This advanced chemical intermediate is valued for its role as a key building block in the research and development of novel pharmaceutical agents, particularly in the areas of kinase inhibition and targeted therapies. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical synthesis facilities engaged in the creation of new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates targeting specific biological pathways.
• Kinase Inhibitor Research: Used as a core scaffold or intermediate in the development of potential kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Biochemical Research: Acts as a tool compound or reference standard in biochemical assays to study enzyme function and inhibition.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis for constructing complex heterocyclic molecules with specific functionalities.

Basic Information

Product Name	5-{[1-(2-Fluorobenzyl)-1H-Indol-3-Yl]Methylidene}-1,3-Dimethyl-2-Thioxodihydropyrimidine-4,6(1H,5H)-Dione
CAS No.	590380-75-9
Molecular Formula	C22H18FN3O2S
Molecular Weight	407.46 g/mol
Synonyms	5-[(1-(2-Fluorobenzyl)-1H-indol-3-yl)methylene]-1,3-dimethyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione; 1,3-Dimethyl-5-{[1-(2-fluorobenzyl)-1H-indol-3-yl]methylidene}-2-thioxodihydropyrimidine-4,6(1H,5H)-dione; 590380-75-9; 5-((1-(2-Fluorobenzyl)-1H-indol-3-yl)methylene)-1,3-dimethyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione; 5-{[1-(2-Fluorobenzyl)-1H-Indol-3-Yl]Methylidene}-1,3-Dimethyl-2-Thioxodihydropyrimidine-4,6(1H,5H)-Dione; 5-[(1-(2-Fluorobenzyl)-1H-indol-3-yl)methylene]-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trithione (tautomeric form)
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Quality Control

Our 5-{[1-(2-Fluorobenzyl)-1H-Indol-3-Yl]Methylidene}-1,3-Dimethyl-2-Thioxodihydropyrimidine-4,6(1H,5H)-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange solid powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.