Description

Ethyl 2-[(Cyanoacetyl)Amino]-5-Methylthiophene-3-Carboxylate is a high-purity, specialized organic building block of significant interest in advanced chemical synthesis. This compound serves as a critical intermediate for the development of novel heterocyclic compounds and active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for its unique molecular framework.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel thiophene-based drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with thiophene cores.
• Material Science: Building block for creating specialized polymers, dyes, and organic electronic materials.
• Chemical Synthesis: Versatile intermediate for constructing complex heterocyclic compounds in academic and industrial R&D.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Ethyl 2-[(Cyanoacetyl)Amino]-5-Methylthiophene-3-Carboxylate
CAS No.	590376-44-6
Molecular Formula	C12H12N2O3S
Molecular Weight	264.30 g/mol
Synonyms	Ethyl 2-[(2-cyanoacetyl)amino]-5-methylthiophene-3-carboxylate; 5-Methyl-2-[(cyanoacetyl)amino]thiophene-3-carboxylic Acid Ethyl Ester; 2-[(Cyanoacetyl)amino]-5-methyl-3-thiophenecarboxylic Acid Ethyl Ester; Thiophene-3-carboxylic acid, 2-[(2-cyanoacetyl)amino]-5-methyl-, ethyl ester; Ethyl 2-(2-cyanoacetamido)-5-methylthiophene-3-carboxylate; CAS 590376-44-6
EINECS	Contact for details

Quality Control

Our Ethyl 2-[(Cyanoacetyl)Amino]-5-Methylthiophene-3-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing specifications such as identity (IR, NMR), purity (HPLC), and impurity profiles. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.