Description

2,5-Di-tert-Butyl-1H-Indole-3-Carbaldehyde is a high-purity, functionalized indole derivative characterized by its sterically hindered tert-butyl groups and reactive aldehyde moiety. This compound matters as a versatile and valuable advanced pharmaceutical intermediate and organic synthesis building block, enabling the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry research targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of new pesticides, herbicides, and plant growth regulators due to its functionalized indole core.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport materials or host materials in OLED device fabrication.
• Ligand and Catalyst Development: The aldehyde group allows for the creation of novel Schiff base ligands for metal catalysis and coordination chemistry.
• Polymer and Material Science: Acts as a monomer or functionalizing agent for creating specialty polymers with unique optical or electronic properties.
• Dye and Pigment Intermediate: Utilized in the synthesis of advanced colorants and functional dyes.
• Academic and Industrial Research: A valuable reagent for methodological studies and exploring new chemical reactions in synthetic organic chemistry.

Basic Information

Product Name	2,5-Di-tert-Butyl-1H-Indole-3-Carbaldehyde
CAS No.	590347-37-8
Molecular Formula	C₁₇H₂₃NO
Molecular Weight	257.37 g/mol
Synonyms	2,5-Di-tert-butylindole-3-carboxaldehyde; 2,5-Bis(1,1-dimethylethyl)-1H-indole-3-carboxaldehyde; 1H-Indole-3-carboxaldehyde, 2,5-bis(1,1-dimethylethyl)-; 2,5-Di-tert-butyl-1H-indole-3-carboxaldehyde; 2,5-Di-tert-butylindole-3-aldehyde; 3-Formyl-2,5-di-tert-butylindole; DTBCA (abbreviation); 2,5-DTBC
EINECS	Contact for details

Quality Control

Our 2,5-Di-tert-Butyl-1H-Indole-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We are committed to providing materials that meet the stringent requirements of GMP and ISO standards for advanced research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity, the product should be stored under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.