Description

Cyclopentanemethanol, 2-Hydroxy-1-Phenyl-, (1R,2S)-Rel- (9Ci) is a chiral, non-racemic organic compound of significant interest in advanced synthetic chemistry. This stereochemically defined building block is crucial for the development of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Used as a versatile chiral auxiliary or starting material in stereoselective organic synthesis to construct complex molecular architectures.
• Agrochemical Development: Employed in the synthesis of novel, enantiopure pesticides and herbicides where specific stereochemistry is required for optimal biological activity.
• Catalyst Ligand Precursor: Serves as a foundational structure for developing novel chiral ligands used in homogeneous catalysis (e.g., hydrogenation, cross-coupling).
• Academic & Industrial R&D: A valuable compound for methodological research in organic chemistry and for scaling up new synthetic routes in process chemistry.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, and fragrances that require high stereochemical purity.

Basic Information

Product Name	Cyclopentanemethanol, 2-Hydroxy-1-Phenyl-, (1R,2S)-Rel- (9Ci)
CAS No.	588718-91-6
Molecular Formula	C12H16O2
Molecular Weight	192.26 g/mol
Synonyms	(1R,2S)-rel-2-Hydroxy-1-phenylcyclopentanemethanol; (1R,2S)-rel-1-Phenyl-2-hydroxycyclopentanemethanol; rel-(1R,2S)-2-Hydroxy-1-phenylcyclopentylmethanol; 2-Hydroxy-1-phenylcyclopentanemethanol (rel-(1R,2S)-); Cyclopentanemethanol, 2-hydroxy-1-phenyl-, (1R,2S)-rel-; (1R,2S)-rel-1-Phenylcyclopentane-1,2-dimethanol; Chiral Cyclopentanol Derivative
EINECS	Contact for details

Quality Control

Our Cyclopentanemethanol, 2-Hydroxy-1-Phenyl-, (1R,2S)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. We support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.