Description

Benzo[B]Thiophene-2-Carboxamide, 3-Chloro-4-Fluoro-n-2-Pyrimidinyl- (9Ci) is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile heterocyclic scaffold for creating novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting oncology, antiviral, and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis: Serves as a versatile precursor for the development of more complex heterocyclic compounds and functionalized thiophene derivatives.
• Agrochemical Development: Potential application as an intermediate in the research and synthesis of new crop protection agents and pesticides.
• Material Science Research: Investigated for use in the development of organic electronic materials due to its fused thiophene-pyrimidine structure.

Basic Information

Product Name	Benzo[B]Thiophene-2-Carboxamide, 3-Chloro-4-Fluoro-n-2-Pyrimidinyl- (9Ci)
CAS No.	588675-49-4
Molecular Formula	C13H7ClFN3OS
Molecular Weight	307.73 g/mol
Synonyms	3-Chloro-4-fluoro-N-(pyrimidin-2-yl)benzo[b]thiophene-2-carboxamide; 3-Chloro-4-fluoro-N-2-pyrimidinyl-1-benzothiophene-2-carboxamide; 588675-49-4; Benzo[b]thiophene-2-carboxamide, 3-chloro-4-fluoro-N-2-pyrimidinyl-; 3-Chloro-4-fluoro-N-(pyrimidin-2-yl)-1-benzothiophene-2-carboxamide
EINECS	Contact for details

Quality Control

Our Benzo[B]Thiophene-2-Carboxamide, 3-Chloro-4-Fluoro-n-2-Pyrimidinyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.