Description

Benzo[B]Thiophene-2-Carboxamide, 3-Chloro-4-Fluoro-n-(2-Pyridinylmethyl)- (9Ci) is a high-purity, advanced pharmaceutical intermediate designed for precision synthesis. This compound is critical for research and development in medicinal chemistry, offering a versatile building block for novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to introduce the benzo[b]thiophene pharmacophore into target molecules.
• Biochemical Research: May be utilized in the study of enzyme inhibition or receptor binding assays due to its specific heterocyclic structure.
• Fine Chemical Production: Integral in the cGMP-compliant manufacturing of high-value, low-volume specialty chemicals for the life sciences industry.

Basic Information

Product Name	Benzo[B]Thiophene-2-Carboxamide, 3-Chloro-4-Fluoro-n-(2-Pyridinylmethyl)- (9Ci)
CAS No.	588675-32-5
Molecular Formula	C15H10ClFN2OS
Molecular Weight	320.77 g/mol
Synonyms	3-Chloro-4-fluoro-N-(pyridin-2-ylmethyl)benzo[b]thiophene-2-carboxamide; 3-Chloro-4-fluoro-N-(2-pyridinylmethyl)-1-benzothiophene-2-carboxamide; 588675-32-5; Benzo[b]thiophene-2-carboxamide, 3-chloro-4-fluoro-N-(2-pyridinylmethyl)-; N-(Pyridin-2-ylmethyl)-3-chloro-4-fluorobenzo[b]thiophene-2-carboxamide
EINECS	Contact for details

Quality Control

Our Benzo[B]Thiophene-2-Carboxamide, 3-Chloro-4-Fluoro-n-(2-Pyridinylmethyl)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.