Description

Benzo[B]Thiophene-2-Carboxamide, 3-Chloro-4-Fluoro-n-4-Morpholinyl- (9Ci) is a high-purity, synthetically valuable heterocyclic compound featuring a benzothiophene core functionalized with chloro, fluoro, and morpholinyl carboxamide groups. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate for research and development in medicinal chemistry. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting complex disease pathways.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its unique heterocyclic scaffold.
• Organic Synthesis: Acts as a versatile precursor for further chemical modifications, leveraging its reactive halogen and amide functional groups.
• Biochemical Tool Compound: Potential use in developing enzyme inhibitors or receptor modulators for biochemical and pharmacological screening.
• Agrochemical Research: May be investigated as an intermediate for developing new crop protection agents with specific biological activity.
• Material Science Exploration: The benzothiophene moiety can be of interest in the development of organic electronic materials or advanced polymers.

Basic Information

Product Name	Benzo[B]Thiophene-2-Carboxamide, 3-Chloro-4-Fluoro-n-4-Morpholinyl- (9Ci)
CAS No.	588675-30-3
Molecular Formula	C13H12ClFN2O2S
Molecular Weight	314.76 g/mol
Synonyms	3-Chloro-4-fluoro-N-(morpholin-4-yl)-1-benzothiophene-2-carboxamide; 3-Chloro-4-fluoro-N-morpholin-4-yl-1-benzothiophene-2-carboxamide; 1-Benzothiophene-2-carboxamide, 3-chloro-4-fluoro-N-4-morpholinyl-; 3-Chloro-4-fluoro-N-(4-morpholinyl)-1-benzothiophene-2-carboxamide; N-(Morpholin-4-yl)-3-chloro-4-fluoro-1-benzothiophene-2-carboxamide; 588675-30-3; Benzothiophene carboxamide derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical techniques including HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We operate in compliance with cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.