Description

Benzo[B]Thiophene-2-Carboxamide, 3-Chloro-4-Fluoro-n-(Tricyclo[3.3.1.13,7]Dec-1-Ylmethyl)- (9Ci) is a sophisticated heterocyclic organic compound featuring a unique adamantane-derived substituent, making it a valuable synthetic intermediate for advanced research and development. This compound is specifically engineered for applications requiring high-purity, structurally complex building blocks in pharmaceutical and agrochemical discovery. It is primarily targeted at R&D chemists and process development scientists working in medicinal chemistry, where it serves as a key precursor for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research programs.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization due to its unique adamantyl and halogenated benzothiophene scaffold.
• Agrochemical Development: Acts as a precursor in the creation of new pesticides and herbicides, leveraging its complex molecular architecture for targeted biological activity.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function and protein-ligand interactions.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with specific thermal or optical properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes and scale-up projects.

Basic Information

Product Name	Benzo[B]Thiophene-2-Carboxamide, 3-Chloro-4-Fluoro-n-(Tricyclo[3.3.1.13,7]Dec-1-Ylmethyl)- (9Ci)
CAS No.	588673-78-3
Molecular Formula	C20H21ClFNOS
Molecular Weight	377.90 g/mol
Synonyms	3-Chloro-4-fluoro-N-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-1-benzothiophene-2-carboxamide; 3-Chloro-4-fluoro-N-(1-adamantylmethyl)benzo[b]thiophene-2-carboxamide; N-(Adamantan-1-ylmethyl)-3-chloro-4-fluorobenzo[b]thiophene-2-carboxamide; 588673-78-3; 3-Chloro-4-fluoro-N-(tricyclo[3.3.1.1³,⁷]dec-1-ylmethyl)-1-benzothiophene-2-carboxamide; Benzo[b]thiophene-2-carboxamide, 3-chloro-4-fluoro-N-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-; 3-Chloro-4-fluoro-N-(adamantan-1-ylmethyl)benzo[b]thiophene-2-carboxamide
EINECS	Contact for details

Quality Control

Our production of Benzo[B]Thiophene-2-Carboxamide, 3-Chloro-4-Fluoro-n-(Tricyclo[3.3.1.13,7]Dec-1-Ylmethyl)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research applications. All materials are characterized using advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, supporting compliance with internal quality standards and research documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect this light-sensitive material from degradation and to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.