Description

2-(2-Bromo-4-Ethylphenoxy)-n-(2,3-Dihydro-1H-Indol-1-Ylcarbonothioyl)Acetamide is a specialized organic compound featuring a complex molecular architecture that combines brominated phenoxy, indoline, and thiourea moieties. This structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients. The compound's unique scaffold is designed to impart specific biological activity, making it critical for drug discovery programs targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Medicinal Chemistry Research: Used as a sophisticated building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Agrochemical Research: Acts as an intermediate in the development of new pesticides or herbicides, leveraging its halogenated aromatic system.
• Chemical Biology Probe: Utilized in biochemical assays to study enzyme inhibition or protein-ligand interactions due to its potential pharmacophore elements.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.
• Academic Research: Employed in university and institutional laboratories for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2-(2-Bromo-4-Ethylphenoxy)-n-(2,3-Dihydro-1H-Indol-1-Ylcarbonothioyl)Acetamide
CAS No.	587841-58-5
Molecular Formula	C19H18BrN3O2S
Molecular Weight	432.34 g/mol
Synonyms	2-(2-Bromo-4-ethylphenoxy)-N-[(2,3-dihydro-1H-indol-1-yl)carbothioyl]acetamide; 1-({[2-(2-Bromo-4-ethylphenoxy)acetyl]carbamothioyl})indoline; N-(2,3-Dihydro-1H-indol-1-ylcarbamothioyl)-2-(2-bromo-4-ethylphenoxy)acetamide; Acetamide, 2-(2-bromo-4-ethylphenoxy)-N-[(2,3-dihydro-1H-indol-1-yl)carbothioyl]-; 587841-58-5; Bromo-ethylphenoxy indoline thiourea derivative
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Bromo-4-Ethylphenoxy)-n-(2,3-Dihydro-1H-Indol-1-Ylcarbonothioyl)Acetamide is manufactured under a strict quality management system to ensure consistency and purity for critical R&D and scale-up applications. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to verify identity and quantify purity. Certificates of Analysis (COA) detailing all test results are provided with each shipment and are available upon request. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.