Description

2-tert-Butyl-3-Formyl-1H-Indole-5-Carbonitrile is a high-value, multi-functional indole derivative used as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scale-up synthesis.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides due to its functionalized indole core.
• Material Science Precursor: Serves as a monomer or precursor for organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and target identification.
• Dye & Pigment Synthesis: Acts as an intermediate for creating specialized indole-based colorants and fluorescent markers.
• Academic & Contract Research: Essential for methodological development and novel reaction pathway exploration in university and CRO laboratories.

Basic Information

Product Name	2-tert-Butyl-3-Formyl-1H-Indole-5-Carbonitrile
CAS No.	587828-18-0
Molecular Formula	C₁₄H₁₄N₂O
Molecular Weight	226.28 g/mol
Synonyms	5-Cyano-2-tert-butyl-1H-indole-3-carboxaldehyde; 2-(tert-Butyl)-3-formyl-1H-indole-5-carbonitrile; 1H-Indole-5-carbonitrile, 2-(1,1-dimethylethyl)-3-formyl-; 2-tert-Butylindole-3-carbaldehyde-5-carbonitrile; 2-(tert-Butyl)-1H-indole-3-carbaldehyde-5-carbonitrile; 5-CN-2-tBu-indole-3-CHO
EINECS	Contact for details

Quality Control

Every batch of 2-tert-Butyl-3-Formyl-1H-Indole-5-Carbonitrile is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are supported by comprehensive Certificates of Analysis (COA) detailing all critical parameters. We adhere to cGMP principles where applicable, ensuring reliable supply for research and development as well as scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.