Description

Cyclohexaneethanol, 5-(1,1-Dimethylethyl)-2-Hydroxy-, (1R,2R,5S)-Rel- (9Ci) is a high-purity, stereochemically defined chiral intermediate of significant interest in advanced organic synthesis. Its value lies in its rigid cyclohexaneethanol backbone bearing a tertiary butyl and a hydroxyl group, which serves as a critical building block for constructing complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in areas requiring stereochemical control.
• Agrochemical Synthesis: Used in the production of advanced, high-efficacy pesticides and herbicides where specific stereochemistry impacts biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, including flavors, fragrances, and advanced materials.
• Academic and R&D: A valuable reference standard and starting material for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	Cyclohexaneethanol, 5-(1,1-Dimethylethyl)-2-Hydroxy-, (1R,2R,5S)-Rel- (9Ci)
CAS No.	586977-45-9
Molecular Formula	C12H24O2
Molecular Weight	200.32 g/mol
Synonyms	rel-(1R,2R,5S)-5-tert-Butyl-2-hydroxycyclohexaneethanol; (1R,2R,5S)-rel-5-(tert-Butyl)-2-hydroxycyclohexaneethanol; 5-tert-Butyl-2-hydroxycyclohexaneethanol (rel-(1R,2R,5S)-isomer); 2-(5-tert-Butyl-2-hydroxycyclohexyl)ethanol; Chiral Cyclohexaneethanol Derivative; Bicyclic Alcohol Intermediate; CAS 586977-45-9
EINECS	Contact for details

Quality Control

Our Cyclohexaneethanol, 5-(1,1-Dimethylethyl)-2-Hydroxy-, (1R,2R,5S)-Rel- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (rel-(1R,2R,5S))
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.