Description

Bicyclo[2.2.1]Heptane-2,3-Dimethanamine, (1R,2R,3R,4S)- (9Ci) is a high-purity, stereochemically defined chiral diamine building block. This compound is valued for its rigid, three-dimensional bicyclic framework, which is essential for imparting specific conformational properties in advanced molecular synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and fine chemical industries for applications such as chiral ligand synthesis, asymmetric catalysis, and the development of novel active pharmaceutical ingredients (APIs).

Application

• Chiral Ligand & Catalyst Synthesis: Serves as a key precursor for constructing sophisticated ligands used in asymmetric hydrogenation, cross-coupling, and other enantioselective transformations.
• Pharmaceutical Intermediate: Employed in the research and development of novel therapeutic agents, where its rigid structure can influence drug potency, selectivity, and metabolic stability.
• Advanced Material Research: Used in the synthesis of specialty polymers, dendrimers, or metal-organic frameworks (MOFs) requiring precise spatial geometry.
• Chemical Biology & Probe Development: Acts as a scaffold for creating molecular probes and tools to study biological systems and enzyme mechanisms.
• Academic & Industrial R&D: A critical reagent for methodological development in organic synthesis and catalysis research.

Basic Information

Product Name	Bicyclo[2.2.1]Heptane-2,3-Dimethanamine, (1R,2R,3R,4S)- (9Ci)
CAS No.	586952-58-1
Molecular Formula	C11H20N2
Molecular Weight	180.29 g/mol
Synonyms	(1R,2R,3R,4S)-Bicyclo[2.2.1]heptane-2,3-dimethanamine; (1R,2R,3R,4S)-2,3-Bis(aminomethyl)bicyclo[2.2.1]heptane; endo,endo-2,3-Bis(aminomethyl)norbornane; (1R,2R,3R,4S)-Norbornane-2,3-dimethanamine; Chiral Norbornane Diamine; Stereoisomerically Pure Bicyclic Diamine
EINECS	Contact for details

Quality Control

Our production of Bicyclo[2.2.1]Heptane-2,3-Dimethanamine, (1R,2R,3R,4S)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques, including chiral HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profile is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.