Description

1-Azabicyclo[3.2.1]Octan-3-One,(1R,5R)-(9Ci) is a high-purity, stereochemically defined bicyclic lactam compound. This advanced pharmaceutical intermediate is critical for the synthesis of complex molecules, offering a rigid, three-dimensional scaffold that is highly valuable in modern drug discovery. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in the areas of neurology and infectious diseases.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Neurological Drug Development: A precursor in the research and synthesis of compounds targeting neurological receptors and enzymes.
• Asymmetric Synthesis: Employed as a chiral auxiliary or template in stereoselective chemical reactions to induce desired chirality in final products.
• Chemical Biology Probes: Utilized in the design and creation of molecular probes for studying biological pathways and protein interactions.
• Process Chemistry & Scale-up: Supports route scouting and optimization for the commercial-scale manufacturing of complex molecules.

Basic Information

Product Name	1-Azabicyclo[3.2.1]Octan-3-One,(1R,5R)-(9Ci)
CAS No.	586363-77-1
Molecular Formula	C7H11NO
Molecular Weight	125.17 g/mol
Synonyms	(1R,5R)-1-Azabicyclo[3.2.1]octan-3-one; (1R,5R)-3-Oxo-1-azabicyclo[3.2.1]octane; (1R,5R)-Tropinone; endo-Tropinone; (1R,5R)-8-Azabicyclo[3.2.1]octan-3-one (tautomer); (1R,5R)-8-Methyl-8-azabicyclo[3.2.1]octan-3-one (common misnomer); (1R,5R)-Bicyclo[3.2.1]octan-3-one, 1-aza-
EINECS	Contact for details

Quality Control

Our 1-Azabicyclo[3.2.1]Octan-3-One,(1R,5R)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.