Description

1H-Indole-2-Carboxylic Acid,6-Chloro-4-Fluoro-3-Formyl-,Ethyl Ester is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel, complex molecules, particularly in the pharmaceutical sector. It is primarily needed by research chemists and process development scientists in pharmaceutical, agrochemical, and material science industries for creating active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging its halogenated indole structure.
• Material Science: Serves as a building block for organic electronic materials and advanced polymers due to its conjugated system.
• Academic & Contract Research: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.
• Custom Synthesis: A starting material for the preparation of more complex indole derivatives and fused heterocycles.

Basic Information

Product Name	1H-Indole-2-Carboxylic Acid,6-Chloro-4-Fluoro-3-Formyl-,Ethyl Ester
CAS No.	586337-03-3
Molecular Formula	C12H9ClFNO3
Molecular Weight	269.66 g/mol
Synonyms	6-Chloro-4-fluoro-3-formyl-1H-indole-2-carboxylic acid ethyl ester; Ethyl 6-chloro-4-fluoro-3-formyl-1H-indole-2-carboxylate; 6-Chloro-4-fluoro-1H-indole-2-carboxylic acid, 3-formyl-, ethyl ester; 2-Carbethoxy-6-chloro-4-fluoro-3-formylindole; 586337-03-3; 1H-Indole-2-carboxylic acid, 6-chloro-4-fluoro-3-formyl-, ethyl ester
EINECS	Contact for details

Quality Control

Our production of 1H-Indole-2-Carboxylic Acid,6-Chloro-4-Fluoro-3-Formyl-,Ethyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. All products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.