Description

1H-Indole-2-Carboxylic Acid,6-Fluoro-3-Formyl-,Ethyl Ester is a high-value fluorinated indole derivative, a crucial advanced intermediate in modern organic synthesis. Its molecular architecture, featuring both a formyl and an ester group on the indole scaffold, makes it an indispensable building block for constructing complex heterocyclic compounds. This product is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides with enhanced efficacy and selectivity.
• Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers and organic electronic materials.
• Academic & Contract Research: Essential for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.
• Fluorine Chemistry: A valuable substrate for further fluorination or derivatization reactions, leveraging the reactivity of the fluorine atom and aldehyde group.

Basic Information

Product Name	1H-Indole-2-Carboxylic Acid,6-Fluoro-3-Formyl-,Ethyl Ester
CAS No.	586336-90-5
Molecular Formula	C12H10FNO3
Molecular Weight	235.21 g/mol
Synonyms	6-Fluoro-3-formyl-1H-indole-2-carboxylic acid ethyl ester; Ethyl 6-fluoro-3-formyl-1H-indole-2-carboxylate; 6-Fluoro-1H-indole-2-carboxylic acid, 3-formyl-, ethyl ester; 6-Fluoro-3-formylindole-2-carboxylic acid ethyl ester; 2-Carbethoxy-6-fluoro-3-formylindole; Ethyl 6-fluoro-3-formylindole-2-carboxylate; 586336-90-5
EINECS	Contact for details

Quality Control

Every batch of 1H-Indole-2-Carboxylic Acid,6-Fluoro-3-Formyl-,Ethyl Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.