Description

1H-Indole-2-Carboxylic Acid,4-Fluoro-3-Formyl-,Ethyl Ester is a high-value fluorinated indole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both formyl and ester functional groups on a fluorinated indole core, makes it an essential building block for constructing complex molecules. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly for oncology and central nervous system (CNS) targets.
• Agrochemical Research: Used to develop novel herbicides and pesticides with enhanced activity and selectivity.
• Material Science: Building block for creating specialized organic electronic materials and fluorescent dyes.
• Academic & R&D: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Chemical Synthesis: Utilized in palladium-catalyzed cross-coupling reactions and other advanced organic transformations.

Basic Information

Product Name	1H-Indole-2-Carboxylic Acid,4-Fluoro-3-Formyl-,Ethyl Ester
CAS No.	586336-89-2
Molecular Formula	C₁₂H₁₀FNO₃
Molecular Weight	235.21 g/mol
Synonyms	4-Fluoro-3-formyl-1H-indole-2-carboxylic acid ethyl ester; Ethyl 4-fluoro-3-formyl-1H-indole-2-carboxylate; 4-Fluoro-3-formylindole-2-carboxylic acid ethyl ester; 586336-89-2; 1H-Indole-2-carboxylic acid, 4-fluoro-3-formyl-, ethyl ester; Ethyl 4-fluoro-3-formylindole-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of 1H-Indole-2-Carboxylic Acid,4-Fluoro-3-Formyl-,Ethyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment, and we support custom synthesis to meet specific purity requirements (e.g., >97%, >98%, >99%).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.