Description

1H-Indole-2-Carboxylic Acid, 6-Chloro-3-Formyl-, Ethyl Ester is a high-value, multi-functional indole derivative that serves as a critical synthetic intermediate. Its molecular architecture, featuring both chloro and formyl substituents, makes it a versatile building block for constructing complex heterocyclic systems. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive indole core.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions, such as Suzuki or Heck reactions, to create more complex molecular architectures.
• Material Science Research: Investigated as a monomer or precursor for the development of organic semiconductors and advanced polymeric materials.
• Chemical Biology Probes: Serves as a scaffold for developing fluorescent probes or enzyme inhibitors used in biochemical assays.

Basic Information

Product Name	1H-Indole-2-Carboxylic Acid, 6-Chloro-3-Formyl-, Ethyl Ester
CAS No.	586336-88-1
Molecular Formula	C₁₂H₁₀ClNO₃
Molecular Weight	251.66 g/mol
Synonyms	6-Chloro-3-formyl-1H-indole-2-carboxylic acid ethyl ester; Ethyl 6-chloro-3-formyl-1H-indole-2-carboxylate; 6-Chloro-3-formylindole-2-carboxylic Acid Ethyl Ester; 2-Carbethoxy-6-chloro-3-formylindole; 6-Chloro-3-aldehydo-1H-indole-2-carboxylic acid ethyl ester; 586336-88-1; Ethyl (6-chloro-3-formyl-1H-indol-2-yl)carboxylate
EINECS	Contact for details

Quality Control

Our 1H-Indole-2-Carboxylic Acid, 6-Chloro-3-Formyl-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our commitment to cGMP principles ensures reliable quality for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.