Description

3-Iodo-5-Methyl-6-Nitro-1H-Indazole is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring iodine, nitro, and methyl substituents on the indazole core, makes it a versatile intermediate for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other enzyme-related pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated nitro-heterocyclic structure.
• Material Science: Acts as a building block for creating specialized organic ligands, dyes, and photoactive compounds.
• Chemical Biology: Employed as a probe or tag in bioconjugation chemistry due to the reactivity of the iodine substituent.
• Academic & Contract Research: Essential for methodological studies in cross-coupling reactions, such as Suzuki or Sonogashira couplings, and other halogen-selective transformations.

Basic Information

Product Name	3-Iodo-5-Methyl-6-Nitro-1H-Indazole
CAS No.	586330-45-2
Molecular Formula	C8H6IN3O2
Molecular Weight	303.06 g/mol
Synonyms	3-Iodo-5-methyl-6-nitro-1H-indazole; 5-Methyl-6-nitro-3-iodo-1H-indazole; 1H-Indazole, 3-iodo-5-methyl-6-nitro-; 586330-45-2; 3-Iodo-5-methyl-6-nitroindazole; 6-Nitro-5-methyl-3-iodo-1H-indazole
EINECS	Contact for details

Quality Control

Our 3-Iodo-5-Methyl-6-Nitro-1H-Indazole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.