Description

1H-Indazole-1-Carboxylic Acid,3-Iodo-6-Nitro-,1,1-Dimethylethyl Ester is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key protected intermediate in the development of novel pharmaceutical agents and agrochemicals, enabling complex molecular construction. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate functionalized indazole scaffolds into their target molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require complex heterocyclic cores.
• Chemical Biology Probe Synthesis: The reactive iodo and nitro groups make it a valuable precursor for creating molecular probes and labeled compounds for biological studies.
• Material Science Research: Potential use as a monomer or precursor for advanced functional materials and polymers with specific electronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	1H-Indazole-1-Carboxylic Acid,3-Iodo-6-Nitro-,1,1-Dimethylethyl Ester
CAS No.	586330-18-9
Molecular Formula	C₁₂H₁₂IN₃O₄
Molecular Weight	389.15 g/mol
Synonyms	tert-Butyl 3-iodo-6-nitro-1H-indazole-1-carboxylate; 3-Iodo-6-nitro-1H-indazole-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-3-iodo-6-nitro-1H-indazole; Boc-3-Iodo-6-nitroindazole; tert-Butyl 3-iodo-6-nitroindazole-1-carboxylate; 586330-18-9; 3-Iodo-6-nitro-indazole-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 1H-Indazole-1-Carboxylic Acid,3-Iodo-6-Nitro-,1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.