Description

Methyl 6-Fluoro-1-Oxo-1,2-Dihydroisoquinoline-4-Carboxylate is a high-purity fluorinated isoquinoline derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in enabling the synthesis of novel drug candidates, particularly in therapeutic areas requiring precise molecular scaffolds. This compound is essential for research and development chemists and process scale-up teams within the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging the biological activity of the fluorinated isoquinoline core.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and protein interactions in biochemical research.
• Material Science Precursor: Potential intermediate for the synthesis of organic electronic materials and specialty polymers requiring fluorinated aromatic components.
• Contract Manufacturing & Development (CDMO): Supplied to CDMOs for custom synthesis and process development projects for client-specific molecules.

Basic Information

Product Name	Methyl 6-Fluoro-1-Oxo-1,2-Dihydroisoquinoline-4-Carboxylate
CAS No.	583880-92-6
Molecular Formula	C11H8FNO3
Molecular Weight	221.19 g/mol
Synonyms	6-Fluoro-1-oxo-1,2-dihydroisoquinoline-4-carboxylic acid methyl ester; Methyl 6-fluoro-1,2-dihydro-1-oxo-4-isoquinolinecarboxylate; 4-Carbomethoxy-6-fluoro-1,2-dihydro-1-oxoisoquinoline; 6-Fluoro-1-oxo-1,2-dihydro-4-isoquinolinecarboxylic acid methyl ester; 6-Fluoro-1-oxo-1,2-dihydroisoquinoline-4-carboxylate methyl ester; 6-Fluoro-1H-isoquinoline-1-one-4-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 6-Fluoro-1-Oxo-1,2-Dihydroisoquinoline-4-Carboxylate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.