Description

6-Methoxy-2-Methyl-1-(Phenylsulfonyl)-1H-Indole is a high-purity, advanced pharmaceutical intermediate characterized by its sulfonylated indole core structure. This compound is of significant value in organic synthesis, serving as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Organic Synthesis Building Block: Used in palladium-catalyzed cross-coupling reactions, such as Suzuki and Heck reactions, to construct more complex molecular architectures.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive indole scaffold.
• Material Science: Investigated as a monomer or additive for creating specialized polymers with unique electronic or photophysical properties.
• Academic & R&D: Serves as a standard or starting material in university and corporate research laboratories for methodological studies and novel compound library generation.

Basic Information

Product Name	6-Methoxy-2-Methyl-1-(Phenylsulfonyl)-1H-Indole
CAS No.	582319-12-8
Molecular Formula	C₁₆H₁₅NO₃S
Molecular Weight	301.36 g/mol
Synonyms	1-(Phenylsulfonyl)-6-methoxy-2-methyl-1H-indole; 6-Methoxy-2-methyl-1-(phenylsulfonyl)indole; 1H-Indole, 6-methoxy-2-methyl-1-(phenylsulfonyl)-; 2-Methyl-6-methoxy-1-(phenylsulfonyl)indole; 1-Benzenesulfonyl-6-methoxy-2-methylindole; 6-Methoxy-2-methyl-1-tosylindole (common name variant); 582319-12-8; 6-Methoxy-2-methylindole-1-sulfonylbenzene
EINECS	Contact for details

Quality Control

Our 6-Methoxy-2-Methyl-1-(Phenylsulfonyl)-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.