Description

5-Bromo-3-Iodo-1-(Phenylsulfonyl)Indole is a high-purity, multi-halogenated indole derivative designed for advanced synthetic chemistry and pharmaceutical research. This compound serves as a versatile and critical building block for constructing complex molecular architectures, particularly in medicinal chemistry and materials science. It is essential for researchers and process chemists in pharmaceutical development, agrochemical research, and organic electronics who require reliable, high-quality intermediates for lead optimization and novel compound synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other biologically relevant indole-based scaffolds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead compound optimization due to its reactive bromo and iodo handles for cross-coupling reactions.
• Agrochemical Development: Serves as a building block for creating new active ingredients in crop protection agents.
• Organic Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Heck) to introduce complex indole motifs into target molecules.
• Material Science: A potential monomer or precursor for functional organic materials, such as organic semiconductors or light-emitting diodes (OLEDs).
• Chemical Biology: Useful for synthesizing molecular probes and labeled compounds for biochemical assays and imaging studies.

Basic Information

Product Name	5-Bromo-3-Iodo-1-(Phenylsulfonyl)Indole
CAS No.	582305-43-9
Molecular Formula	C14H9BrINO2S
Molecular Weight	461.10 g/mol
Synonyms	1-(Benzenesulfonyl)-5-bromo-3-iodo-1H-indole; 5-Bromo-3-iodo-1H-indole 1-(phenylsulfonyl); 5-Bromo-3-iodo-1-(phenylsulfonyl)-1H-indole; 1H-Indole, 5-bromo-3-iodo-1-(phenylsulfonyl)-; 5-Br-3-I-1-PSI; 5-Bromo-3-iodo-1-(benzenesulfonyl)indole
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Iodo-1-(Phenylsulfonyl)Indole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.