Description

1-(4-(Trifluoromethyl)Benzyl)-3-(Isoquinolin-5-Yl)Urea is a high-purity synthetic organic compound featuring a unique molecular architecture combining a trifluoromethylbenzyl group with an isoquinoline-urea core. This compound is valued for its role as a key chemical intermediate and a versatile scaffold in advanced research and development. It is primarily utilized by pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional molecules. Its specific structure makes it a critical building block for developing compounds with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of potential drug candidates, particularly for oncology, neurology, and anti-inflammatory research.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging the biological activity of the isoquinoline and urea motifs.
• Chemical Biology Probe: Acts as a scaffold for creating molecular probes to study enzyme function and protein-protein interactions in biological systems.
• Material Science Precursor: Employed in the research and development of advanced organic materials, such as organic semiconductors or metal-organic frameworks (MOFs).
• Academic & Contract Research: Essential for medicinal chemistry programs in academic institutions and contract research organizations (CROs) focused on heterocyclic chemistry.
• Custom Synthesis Starting Material: Provides a specialized starting point for custom synthesis services aiming to create libraries of derivatives for high-throughput screening.

Basic Information

Product Name	1-(4-(Trifluoromethyl)Benzyl)-3-(Isoquinolin-5-Yl)Urea
CAS No.	581809-67-8
Molecular Formula	C18H14F3N3O
Molecular Weight	345.32 g/mol
Synonyms	5-Isoquinolinamine, N-[[4-(trifluoromethyl)phenyl]methyl]-N'-carbamoyl-; Urea, N-[[4-(trifluoromethyl)phenyl]methyl]-N'-(5-isoquinolinyl)-; 1-[(4-Trifluoromethylbenzyl)]-3-(isoquinolin-5-yl)urea; N-(4-(Trifluoromethyl)benzyl)-N'-(isoquinolin-5-yl)urea; 5-[[[[4-(Trifluoromethyl)phenyl]methyl]amino]carbonyl]amino]isoquinoline; 581809-67-8; TFM-Isoquinoline Urea
EINECS	Contact for details

Quality Control

Our 1-(4-(Trifluoromethyl)Benzyl)-3-(Isoquinolin-5-Yl)Urea is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to current industry best practices, and each lot is accompanied by a comprehensive Certificate of Analysis (COA). The COA provides detailed results for identity, purity (typically ≥95% by HPLC), and impurity profile, ensuring the material meets the stringent requirements for research and development applications. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.