Description

2-Methylpyridine-4-Boronic Acid is a versatile organoboron building block, specifically a pyridine-substituted boronic acid. This compound is essential for modern synthetic chemistry, enabling the formation of carbon-carbon bonds through cross-coupling reactions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing complex drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used to create novel pesticides, herbicides, and fungicides with enhanced efficacy and selectivity.
• Material Science Research: Serves as a building block for constructing organic frameworks, ligands for catalysts, and advanced polymers.
• Chemical Biology & Diagnostics: Employed in the development of molecular probes, sensors, and bioconjugates.
• Catalyst Ligand Synthesis: Used to prepare specialized pyridine-based ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A critical raw material for custom synthesis houses serving diverse R&D and scale-up projects.

Basic Information

Product Name	2-Methylpyridine-4-Boronic Acid
CAS No.	579476-63-4
Molecular Formula	C6H8BNO2
Molecular Weight	136.95 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-picoline; 2-Picoline-4-boronic acid; (2-Methylpyridin-4-yl)boronic acid; 2-Methyl-4-pyridineboronic acid; 4-Borono-2-methylpyridine; 2-Methyl-4-pyridinylboronic acid; 2-Methylisonicotinic acid boronate
EINECS	Contact for details

Quality Control

Our 2-Methylpyridine-4-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.