Description

Bicyclo[4.2.1]Non-3-En-9-One, 8-Ethyl-1,3,6-Trimethyl-, (1R,6S,8S)-Rel- (9Ci) is a high-purity, stereochemically defined bicyclic ketone building block of significant interest in advanced organic synthesis. Its unique, rigid molecular framework makes it a valuable chiral intermediate for constructing complex natural products and active pharmaceutical ingredients (APIs). This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds with specific three-dimensional architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, particularly for complex small-molecule drugs.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides where its specific stereochemistry can influence biological activity.
• Material Science Research: Acts as a precursor for developing specialty polymers or liquid crystals with tailored properties.
• Catalyst & Ligand Development: Employed in the synthesis of novel chiral catalysts and ligands for asymmetric synthesis.
• Academic & Industrial R&D: A critical tool for methodological studies in organic chemistry, including cycloaddition reactions and ring transformation studies.
• Flavor & Fragrance Industry: Potential use as an intermediate for synthesizing complex, naturally occurring scent and flavor molecules.

Basic Information

Product Name	Bicyclo[4.2.1]Non-3-En-9-One, 8-Ethyl-1,3,6-Trimethyl-, (1R,6S,8S)-Rel- (9Ci)
CAS No.	578714-80-4
Molecular Formula	C14H22O
Molecular Weight	206.33 g/mol
Synonyms	rel-(1R,6S,8S)-8-Ethyl-1,3,6-trimethylbicyclo[4.2.1]non-3-en-9-one; (1R,6S,8S)-rel-8-Ethyl-1,3,6-trimethylbicyclo[4.2.1]non-3-en-9-one; Bicyclo[4.2.1]non-3-en-9-one, 8-ethyl-1,3,6-trimethyl-, (1R,6S,8S)-rel-; 8-Ethyl-1,3,6-trimethylbicyclo[4.2.1]non-3-en-9-one (relative stereochemistry); Chiral Bicyclic Ketone Intermediate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Each batch is characterized using advanced analytical techniques including GC, HPLC, NMR, and chiral analysis to ensure high chemical and stereochemical purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support cGMP and ISO 9001 compliant manufacturing for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to prevent degradation. Handle and store in accordance with all applicable regulations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Standard Grade)
Chiral Purity (Chiral HPLC/GC)	≥ 98.0% de (Diastereomeric excess)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.