Description

6-Chloro-2-(Piperidin-4-Yl)-1H-Benzo[D]Imidazole is a high-value, heterocyclic organic compound featuring a fused benzimidazole core substituted with a chloro group and a piperidine moiety. This specific molecular architecture makes it a critical pharmacological intermediate and a versatile building block in advanced organic synthesis. It is primarily sought after by pharmaceutical R&D organizations and fine chemical manufacturers engaged in developing novel therapeutic agents, particularly in the areas of kinase inhibitors and receptor modulators.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates targeting various diseases.
• Kinase Inhibitor Research: Used as a core scaffold or a functionalized fragment in the development of novel kinase inhibitors for oncology and inflammatory disorders.
• Chemical Biology & Proteomics: Employed in the design and synthesis of chemical probes for studying enzyme function and protein-ligand interactions.
• Medicinal Chemistry: Utilized for structure-activity relationship (SAR) studies and lead optimization programs due to its modifiable piperidine and chloro substituents.
• Fine Chemical Synthesis: Acts as a specialized building block for constructing complex heterocyclic compounds in custom synthesis and contract manufacturing.
• Agrochemical Research: Potential application as an intermediate in the development of new active ingredients for crop protection.

Basic Information

Product Name	6-Chloro-2-(Piperidin-4-Yl)-1H-Benzo[D]Imidazole
CAS No.	578709-06-5
Molecular Formula	C12H14ClN3
Molecular Weight	235.71 g/mol
Synonyms	6-Chloro-2-(4-piperidinyl)-1H-benzimidazole; 2-(4-Piperidinyl)-6-chloro-1H-benzimidazole; 6-Chloro-2-piperidin-4-yl-1H-benzoimidazole; 6-Chloro-2-(piperidin-4-yl)-1H-benzo[d]imidazole; 1H-Benzimidazole, 6-chloro-2-(4-piperidinyl)-; 578709-06-5; 6-Chloro-2-(4-piperidyl)-1H-benzimidazole
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-(Piperidin-4-Yl)-1H-Benzo[D]Imidazole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.