Description

2-Benzofurancarboxamide,n-[(4-Chlorophenyl)Methyl]-3,6-Dimethyl-n-(Tetrahydro-1,1-Dioxido-3-Thienyl)-(9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research and development targeting specific therapeutic areas. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of proprietary drug candidates, especially in central nervous system (CNS) and metabolic disorder research.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Process Development & Scale-up: Employed in optimizing synthetic routes from laboratory scale to pilot plant and commercial production for new chemical entities (NCEs).
• Reference Standard: Utilized as an analytical standard for quality control, method development, and regulatory submissions in API manufacturing.
• Biochemical Research: Potential application in probing biological pathways and enzyme interactions due to its specific benzofuran-thiophene sulfone pharmacophore.

Basic Information

Product Name	2-Benzofurancarboxamide,n-[(4-Chlorophenyl)Methyl]-3,6-Dimethyl-n-(Tetrahydro-1,1-Dioxido-3-Thienyl)-(9Ci)
CAS No.	577998-85-7
Molecular Formula	C22H23ClN2O4S
Molecular Weight	446.95 g/mol
Synonyms	N-[(4-Chlorophenyl)methyl]-3,6-dimethyl-N-(1,1-dioxo-1λ⁶-thiolan-3-yl)-1-benzofuran-2-carboxamide; 1-Benzofuran-2-carboxamide, N-[(4-chlorophenyl)methyl]-3,6-dimethyl-N-(tetrahydro-1,1-dioxido-3-thienyl)- (9CI); 3,6-Dimethyl-N-(4-chlorobenzyl)-N-(1,1-dioxothiolan-3-yl)benzofuran-2-carboxamide; 577998-85-7; UNII-9F8K3F4V4I; 9F8K3F4V4I
EINECS	Contact for details

Quality Control

Our 2-Benzofurancarboxamide,n-[(4-Chlorophenyl)Methyl]-3,6-Dimethyl-n-(Tetrahydro-1,1-Dioxido-3-Thienyl)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are available for every lot upon request, supporting your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.