Description

Bicyclo[5.1.0]Octane-8-Carboxylic Acid, 8-Amino-, (1Alpha,7Alpha,8Alpha)- (9Ci) is a high-purity, advanced pharmaceutical intermediate featuring a unique strained bicyclic scaffold. This compound is valued for its role as a critical building block in the synthesis of novel, complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas requiring sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel targets.
• Protease Inhibitor Synthesis: Serves as a core structural element in the synthesis of potential protease inhibitors.
• Complex Molecule Construction: Utilized in organic synthesis to introduce conformational constraint and stereochemical complexity.
• Chemical Biology Probes: Acts as a precursor for labeled compounds used in biochemical and cellular assays.
• Academic & Industrial R&D: Employed in exploratory chemistry for developing new synthetic methodologies.

Basic Information

Item	Detail
Product Name	Bicyclo[5.1.0]Octane-8-Carboxylic Acid, 8-Amino-, (1Alpha,7Alpha,8Alpha)- (9Ci)
CAS No.	577968-09-3
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	(1α,7α,8α)-8-Aminobicyclo[5.1.0]octane-8-carboxylic acid; 8-Aminobicyclo[5.1.0]octane-8-carboxylic acid (1α,7α,8α)-; Bicyclo[5.1.0]octane-8-carboxylic acid, 8-amino-, (1α,7α,8α)-; 577968-09-3; (1alpha,7alpha,8alpha)-8-Aminobicyclo[5.1.0]octane-8-carboxylic acid; 8-Aza-bicyclo[5.1.0]octane-8-carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our Bicyclo[5.1.0]Octane-8-Carboxylic Acid, 8-Amino-, (1Alpha,7Alpha,8Alpha)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure identity, potency, and purity meet exacting standards for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.