Description

Methyl 3-{[(1E)-(Dimethylamino)Methylene]Amino}-6-Methoxy-1H-Indole-2-Carboxylate is a high-value, specialized indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its molecular architecture, featuring a reactive formamidine group, makes it an essential building block for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). This compound is primarily sought after by research institutions and pharmaceutical development teams engaged in the synthesis of novel drug candidates, particularly in oncology and neurological research.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex indole-based drug molecules and investigational new chemical entities.
• Organic Synthesis Building Block: Utilized in palladium-catalyzed cross-coupling reactions, cyclization reactions, and as a scaffold for constructing fused polyheterocycles.
• Agrochemical Research: Employed in the development of new crop protection agents and plant growth regulators that leverage the indole core structure.
• Material Science Research: Investigated as a monomer or functional component in the creation of advanced organic electronic materials and dyes.
• Academic & Contract Research: Serves as a standard reagent in university laboratories and CROs (Contract Research Organizations) for methodological development and discovery chemistry.

Basic Information

Product Name	Methyl 3-{[(1E)-(Dimethylamino)Methylene]Amino}-6-Methoxy-1H-Indole-2-Carboxylate
CAS No.	573950-58-0
Molecular Formula	C14H17N3O3
Molecular Weight	275.31 g/mol
Synonyms	Methyl (E)-3-((dimethylamino)methyleneamino)-6-methoxy-1H-indole-2-carboxylate; Methyl 3-[(E)-(dimethylamino)methylideneamino]-6-methoxy-1H-indole-2-carboxylate; 6-Methoxy-3-[(E)-(dimethylamino)methylideneamino]-1H-indole-2-carboxylic acid methyl ester; 3-[(Dimethylamino)methylideneamino]-6-methoxy-1H-indole-2-carboxylic acid methyl ester; CAS 573950-58-0; Indole-2-carboxylate derivative; Vilsmeier reagent adduct intermediate
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-{[(1E)-(Dimethylamino)Methylene]Amino}-6-Methoxy-1H-Indole-2-Carboxylate is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.