Description

5-Bromo-3-Hydroxyisoindolin-1-One is a high-purity, synthetically valuable heterocyclic building block. This compound matters as a key intermediate in the development of advanced pharmaceutical agents and functional organic materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial synthon for the synthesis of novel isoindolinone-based drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the brominated isoindolinone scaffold.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or host materials in OLED device fabrication due to its rigid, functionalizable structure.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the discovery of new chemical entities.
• Fine Chemical Production: Acts as a building block for the manufacture of dyes, pigments, and other performance chemicals.

Basic Information

Product Name	5-Bromo-3-Hydroxyisoindolin-1-One
CAS No.	573675-39-5
Molecular Formula	C8H6BrNO2
Molecular Weight	228.04 g/mol
Synonyms	5-Bromo-3-hydroxy-2,3-dihydro-1H-isoindol-1-one; 3-Hydroxy-5-bromo-isoindolin-1-one; 1H-Isoindol-1-one, 5-bromo-2,3-dihydro-3-hydroxy-; 5-Bromo-3-hydroxyisoindolinone; 573675-39-5; 5-Bromo-3-hydroxy-1-isoindolinone
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Hydroxyisoindolin-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic nature, store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage, consider using desiccants or storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.