Description

4-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Morpholine is a high-purity, advanced pharmaceutical intermediate and building block featuring a morpholine-substituted phenylboronic ester. This compound is critical for enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern medicinal chemistry and materials science. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries to construct complex molecular architectures efficiently.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in oncology and CNS research.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds to create biaryl structures, essential for drug discovery and material science.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport materials and emissive layer components in display technology.
• Ligand and Catalyst Development: Employed in the design of novel ligands for transition metal catalysis and organocatalysts.
• Polymer and Material Science: A monomer for creating functional polymers with specific electronic or mechanical properties.
• Chemical Biology Probes: Used to synthesize tagged molecules for studying biological pathways and protein interactions.

Basic Information

Item	Details
Product Name	4-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Morpholine
CAS No.	568577-88-8
Molecular Formula	C16H24BNO3
Molecular Weight	289.18 g/mol
Synonyms	4-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)morpholine; 4-Morpholinophenylboronic acid pinacol ester; [4-(Morpholin-4-yl)phenyl]boronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-phenylmorpholine; 2-(4-Morpholinophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 4-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Morpholine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance for critical coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.