Description

1H-Indazole-5-Carboxylic Acid is a high-purity heterocyclic building block of significant importance in modern organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical agents and advanced materials. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a precursor for organic ligands in metal-organic frameworks (MOFs) and functional polymers.
• Biochemical Tool Compound: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.

Basic Information

Product Name	1H-Indazole-5-Carboxylic Acid
CAS No.	561700-61-6
Molecular Formula	C8H6N2O2
Molecular Weight	162.15 g/mol
Synonyms	5-Indazolecarboxylic Acid; 1H-Indazole-5-carboxylic acid; Indazole-5-carboxylic acid; 5-Carboxyindazole; 1H-Indazol-5-ylcarboxylic acid; 5-(1H-Indazole)carboxylic Acid; 1H-Indazole-5-carboxylic acid (9CI)
EINECS	Contact for details

Quality Control

Our 1H-Indazole-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.