Description

4,4'-Di-n-Acetylamino-Diphenylsulfoxide-D8 is a deuterated isotopologue of a key sulfoxide-based intermediate, distinguished by its high isotopic purity. This compound is critical for applications requiring precise molecular tracking and reduced metabolic interference, offering enhanced stability and specificity in analytical and synthetic workflows. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the development of deuterated active ingredients and as an internal standard in mass spectrometry.

Application

• Pharmaceutical Research & Development: As a deuterated building block for the synthesis of novel drug candidates, leveraging the kinetic isotope effect to potentially improve metabolic stability and bioavailability.
• Analytical Chemistry: Serving as a high-purity internal standard for quantitative analysis via Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS), ensuring accurate measurement in complex matrices.
• Metabolic Studies: Used in tracer studies to investigate drug metabolism pathways and pharmacokinetics with greater precision due to its isotopic label.
• Agrochemical Innovation: As a precursor in the development of deuterated pesticides and herbicides, where isotopic substitution can alter environmental degradation profiles.
• Material Science: Potential use in the synthesis of specialized polymers or organic electronic materials where deuterium incorporation can modify physical properties.
• Contract Research Organizations (CROs): A vital reagent for client projects requiring labeled compounds for regulatory submission support and advanced testing.

Basic Information

Product Name	4,4'-Di-n-Acetylamino-Diphenylsulfoxide-D8
CAS No.	557794-36-2
Molecular Formula	C₁₆H₁₀D₈N₂O₃S
Molecular Weight	318.42 g/mol
Synonyms	N,N'-(Sulfinylbis(4,1-phenylene))bis(acetamide)-d8; Bis(4-acetamidophenyl) sulfoxide-d8; 4,4'-Sulfinyldiacetanilide-d8; 4-Acetamidophenyl 4-acetamidophenyl sulfoxide-d8; 4,4'-Diacetamidodiphenyl sulfoxide-d8; Deuterated DADPS-O; [D8]-4,4'-Diacetamidodiphenylsulfoxide
EINECS	Contact for details

Quality Control

Every batch of 4,4'-Di-n-Acetylamino-Diphenylsulfoxide-D8 is manufactured and tested under a strict quality management system. We guarantee high chemical and isotopic purity, verified by advanced spectroscopic and chromatographic methods. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and impurity profiles is provided with each shipment to ensure compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider using inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.