Description

6-Bromo-5-Nitroindolin-2-One is a high-purity, advanced pharmaceutical intermediate characterized by its halogenated and nitrated indolinone core structure. This compound is of significant value for its role as a versatile building block in the synthesis of complex, biologically active molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new drug candidates, especially those targeting kinase inhibition and other therapeutic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Serves as a crucial scaffold for structure-activity relationship (SAR) studies and the development of targeted small-molecule therapies.
• Kinase Inhibitor Development: Used in the construction of heterocyclic cores found in potential inhibitors for various kinases, a major class of therapeutic targets.
• Chemical Synthesis Building Block: Utilized in organic synthesis for introducing bromo and nitro functional groups into complex molecular architectures.
• Agrochemical Research: May be employed in the research and development of new agrochemicals and plant protection agents.

Basic Information

Product Name	6-Bromo-5-Nitroindolin-2-One
CAS No.	557093-47-7
Molecular Formula	C8H5BrN2O3
Molecular Weight	257.04 g/mol
Synonyms	6-Bromo-5-nitro-2,3-dihydro-1H-indol-2-one; 5-Nitro-6-bromoindolin-2-one; 2-Indolinone, 6-bromo-5-nitro-; 6-Bromo-5-nitroindolin-2-one; 6-Bromo-5-nitro-2-indolinone
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-Nitroindolin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.