Description

(R)-Binaphthylisopropylphosphite CAS NO 557089-90-4 is a chiral organophosphorus compound widely utilized as a versatile ligand in asymmetric catalysis. Its value lies in its ability to induce high enantioselectivity in critical synthetic transformations, enabling the production of optically pure intermediates. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control.

Application

• As a chiral ligand in asymmetric hydrogenation and hydroformylation reactions.
• Catalyst component for the synthesis of enantiomerically pure pharmaceutical intermediates.
• Use in the preparation of chiral agrochemicals and flavors/fragrances.
• Key reagent in academic and industrial research for developing new catalytic methodologies.
• Asymmetric allylic substitution and conjugate addition reactions.
• Co-catalyst in transition metal-catalyzed cross-coupling reactions.

Basic Information

Product Name	(R)-Binaphthylisopropylphosphite
CAS No.	557089-90-4
Molecular Formula	C23H19O3P
Molecular Weight	374.37 g/mol
Synonyms	(R)-2,2'-Bis(diisopropoxyphosphino)-1,1'-binaphthyl; (R)-BINAP(O-iPr)2; (R)-2,2'-Bis(diisopropylphosphito)-1,1'-binaphthyl; (R)-BINAP Diphosphite; (R)-BINOL-Derived Phosphite Ligand; (R)-H8-BINAP(O-iPr)2 (if hydrogenated); (R)-1,1'-Binaphthalene-2,2'-diyl bis(diisopropyl phosphite)
EINECS	Contact for details

Quality Control

Our (R)-Binaphthylisopropylphosphite is manufactured under strict quality control protocols to ensure high chemical purity and enantiomeric excess (ee) suitable for demanding catalytic applications. Each batch is characterized by advanced analytical techniques, including NMR, HPLC, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and enantiomeric purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C to minimize oxidation and hydrolysis. The product is hygroscopic and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.