Description

4-Ethyl 2-(2-Methoxyethyl) 5-Amino-3-Methylthiophene-2,4-Dicarboxylate is a high-purity, functionalized thiophene derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and critical building block for constructing complex heterocyclic systems, particularly in the development of novel active pharmaceutical ingredients (APIs) and specialty materials. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to create new molecules with tailored properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides where the thiophene core imparts specific biological activity.
• Material Science Research: Acts as a monomer or functional unit in the development of advanced organic electronic materials, such as conductive polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Dye and Pigment Chemistry: Employed in the synthesis of specialized dyes and pigments due to the chromophoric properties of the aminothiophene structure.
• Chemical Research & Development: A valuable scaffold for medicinal chemistry and process chemistry for exploring structure-activity relationships (SAR) and optimizing synthetic routes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.

Basic Information

Product Name	4-Ethyl 2-(2-Methoxyethyl) 5-Amino-3-Methylthiophene-2,4-Dicarboxylate
CAS No.	556016-30-9
Molecular Formula	C14H21NO5S
Molecular Weight	315.39 g/mol
Synonyms	5-Amino-3-methylthiophene-2,4-dicarboxylic acid 4-ethyl 2-(2-methoxyethyl) ester; Ethyl 5-amino-3-methyl-2-[(2-methoxyethoxy)carbonyl]thiophene-4-carboxylate; 5-Amino-3-methylthiophene-2,4-dicarboxylic acid diethyl ester derivative; Aminomethylthiophene dicarboxylate ester; CAS 556016-30-9; Thiophene-2,4-dicarboxylate intermediate
EINECS	Contact for details

Quality Control

Our 4-Ethyl 2-(2-Methoxyethyl) 5-Amino-3-Methylthiophene-2,4-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.