Description

5-(5-Chloro-2-Methoxy-Phenyl)-4H-[1,2,4]Triazole-3-Thiol is a high-purity heterocyclic building block and key synthetic intermediate of significant commercial interest. This compound is valued for its versatile triazole-thiol functional group, which is critical for constructing molecules with specific biological and material science properties. It is primarily sought by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold in the research and development of new drug candidates, particularly for antivirals, antifungals, and enzyme inhibitors.
• Agrochemical Synthesis: Used as a key precursor in the manufacture of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Employed in the development of novel polymers, ligands for metal complexes, and advanced organic electronic materials.
• Chemical Biology: Acts as a versatile building block for creating probes, inhibitors, and other tools for biochemical and cellular research.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	5-(5-Chloro-2-Methoxy-Phenyl)-4H-[1,2,4]Triazole-3-Thiol
CAS No.	554423-96-0
Molecular Formula	C9H8ClN3OS
Molecular Weight	241.70 g/mol
Synonyms	5-(5-Chloro-2-methoxyphenyl)-4H-1,2,4-triazole-3-thiol; 5-(5-Chloro-2-methoxyphenyl)-1,2,4-triazole-3-thiol; 3-Mercapto-5-(5-chloro-2-methoxyphenyl)-1,2,4-triazole; 5-(5-Chloro-2-methoxy-phenyl)-2,4-dihydro-[1,2,4]triazole-3-thione; 554423-96-0; 5-(5-Chloro-2-methoxyphenyl)-3-mercapto-1,2,4-triazole
EINECS	Contact for details

Quality Control

Our production of 5-(5-Chloro-2-Methoxy-Phenyl)-4H-[1,2,4]Triazole-3-Thiol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC, GC, and NMR. We support cGMP and ISO 9001 compliant manufacturing for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.