Description

2-[(2-Chloroacetyl)Amino]-4-(2-Chlorophenyl)-3-Thiophenecarboxylic Acid Ethyl Ester is a high-purity, synthetically valuable chemical intermediate characterized by its distinct thiophene and chlorophenyl backbone. This compound is critical for research and development in advanced organic synthesis, where it serves as a versatile building block for constructing complex molecular architectures. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory pathways.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging its heterocyclic structure for biological activity.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, amide bond formations, and cyclization processes to create complex heterocyclic compounds.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic electronic materials due to the thiophene moiety.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2-[(2-Chloroacetyl)Amino]-4-(2-Chlorophenyl)-3-Thiophenecarboxylic Acid Ethyl Ester
CAS No.	554404-40-9
Molecular Formula	C15H13Cl2NO3S
Molecular Weight	358.24 g/mol
Synonyms	Ethyl 2-[(2-chloroacetyl)amino]-4-(2-chlorophenyl)thiophene-3-carboxylate; 2-(2-Chloroacetamido)-4-(2-chlorophenyl)thiophene-3-carboxylic Acid Ethyl Ester; 4-(2-Chlorophenyl)-2-[(2-chloroacetyl)amino]thiophene-3-carboxylic Acid Ethyl Ester; 2-Chloro-N-[4-(2-chlorophenyl)-3-(ethoxycarbonyl)thiophen-2-yl]acetamide; AKOS BRN 0975; ZINC000257098509; ACH-00002945; EN300-125664
EINECS	Contact for details

Quality Control

Our 2-[(2-Chloroacetyl)Amino]-4-(2-Chlorophenyl)-3-Thiophenecarboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) documenting all test results is provided with each shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.