Description

2-(5-Bromo-2-Pyridinyl)-1,2,3,4-Tetrahydroisoquinoline is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel therapeutic agents and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry research for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic scaffold for bioactivity.
• Ligand Synthesis: Acts as a starting material for creating novel ligands in catalysis and coordination chemistry.
• Material Science: Employed in the research and development of organic electronic materials and photoactive compounds.
• Chemical Biology Probes: Utilized as a scaffold for designing molecular probes to study biological pathways and protein functions.
• Custom Synthesis: A fundamental component for contract research organizations (CROs) and CDMOs performing bespoke synthetic routes for clients.

Basic Information

Product Name	2-(5-Bromo-2-Pyridinyl)-1,2,3,4-Tetrahydroisoquinoline
CAS No.	553679-54-2
Molecular Formula	C14H13BrN2
Molecular Weight	289.17 g/mol
Synonyms	5-Bromo-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)pyridine; 2-(5-Bromopyridin-2-yl)-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-2-(5-bromo-2-pyridinyl)isoquinoline; 553679-54-2; 2-(5-Bromo-2-pyridyl)-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our 2-(5-Bromo-2-Pyridinyl)-1,2,3,4-Tetrahydroisoquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.