Description

n-Boc-6-Bromoisoquinolin-1-Amine is a high-purity, protected heterocyclic amine building block of significant importance in modern synthetic chemistry. Its core value lies in providing a versatile and reactive scaffold for the construction of complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process R&D teams engaged in the synthesis of novel drug candidates, agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Medicinal Chemistry Research: Serves as a crucial building block for constructing compound libraries and exploring structure-activity relationships (SAR) in drug discovery.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the isoquinoline core.
• Organic Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a protected amine for sequential functionalization.
• Material Science: Potential monomer or precursor for the synthesis of specialty polymers and organic electronic materials.

Basic Information

Product Name	n-Boc-6-Bromoisoquinolin-1-Amine
CAS No.	552331-12-1
Molecular Formula	C₁₄H₁₅BrN₂O₂
Molecular Weight	323.19 g/mol
Synonyms	1-Amino-6-bromoisoquinoline, N-Boc protected; tert-Butyl (6-bromo-1-isoquinolyl)carbamate; 6-Bromo-1-isoquinolinamine, N-Boc derivative; (6-Bromoisoquinolin-1-yl)carbamic acid tert-butyl ester; Boc-6-Br-IQ-1-NH₂; N-(tert-Butoxycarbonyl)-6-bromoisoquinolin-1-amine; 552331-12-1; Carbamic acid, N-(6-bromo-1-isoquinolinyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our n-Boc-6-Bromoisoquinolin-1-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Our quality commitment aligns with the standards expected for fine chemical and pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC Area %)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.