Description

4-(5-Bromo-1H-Indol-3-Yl)-2-Butanone is a specialized brominated indole derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile molecular scaffold for constructing complex heterocyclic compounds and active pharmaceutical ingredients (APIs). This high-purity building block is essential for researchers and manufacturers in pharmaceutical development, agrochemical research, and advanced material science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in developing new active ingredients for crop protection products, leveraging its heterocyclic structure.
• Chemical Synthesis: Versatile building block for constructing complex indole-based alkaloids and other natural product analogs in medicinal chemistry.
• Material Science: Potential monomer or precursor for specialty polymers and organic electronic materials due to its conjugated system.
• Biochemical Research: Used as a probe or inhibitor in enzymatic studies, given its structural similarity to biologically active indoles.
• Academic & R&D: Serves as a standard or starting material in university and industrial research laboratories for method development and discovery chemistry.

Basic Information

Product Name	4-(5-Bromo-1H-Indol-3-Yl)-2-Butanone
CAS No.	552314-85-9
Molecular Formula	C₁₂H₁₂BrNO
Molecular Weight	266.14 g/mol
Synonyms	5-Bromo-3-(3-oxobutyl)-1H-indole; 1H-Indole, 5-bromo-3-(3-oxobutyl)-; 4-(5-Bromo-1H-indol-3-yl)butan-2-one; 5-Bromo-3-(3-oxobutyl)indole; 4-(5-Bromoindol-3-yl)-2-butanone; 5-Bromotryptophol methyl ketone; 3-(3-Oxobutyl)-5-bromo-1H-indole
EINECS	Contact for details

Quality Control

Our 4-(5-Bromo-1H-Indol-3-Yl)-2-Butanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for every shipment, supporting compliance with cGMP and ICH guidelines for advanced intermediates. Our commitment to traceability and documentation ensures reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH limits
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.