Description

6-Fluoro-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester is a high-purity fluorinated heterocyclic building block essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science: Serves as a monomer or building block for creating specialty polymers and organic electronic materials with tailored properties.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and other transformations to introduce the benzo[b]thiophene scaffold into target molecules.
• Ligand & Catalyst Development: Utilized for constructing complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	6-Fluoro-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester
CAS No.	550998-52-2
Molecular Formula	C10H7FO2S
Molecular Weight	210.22 g/mol
Synonyms	Methyl 6-Fluorobenzo[b]thiophene-2-carboxylate; 6-Fluorobenzo[b]thiophene-2-carboxylic acid methyl ester; 2-Methoxycarbonyl-6-fluorobenzo[b]thiophene; 6-Fluoro-1-benzothiophene-2-carboxylic acid methyl ester; Methyl 6-fluoro-1-benzothiophene-2-carboxylate; 550998-52-2; 6-F-BT-2-COOMe
EINECS	Contact for details

Quality Control

Our 6-Fluoro-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.